Yasmin: Combined Contraceptive Pill

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Yasmin is an oral contraceptive pill that is used to prevent pregnancy. It contains a small amount of two different female hormones, namely drospirenone and ethinyl estradiol.

What is Yasmin used for?

It is used as an oral hormonal contraceptive.

In addition to the properties of contraception, it has other properties. In particular, it produces an antiandrogenic effect, as a result, it has an effect on androgenic alopecia, acne, seborrhea, hormone-dependent fluid retention in the body.

It also has properties of treating the symptoms of the premenstrual dysphoric disorder in women who are using oral contraception.

Ethinylestradiol, which is part of the drug, is able to prevent the onset of osteoporosis by affecting osteoclasts. It also has a beneficial effect on the skin, slows down the formation of wrinkles on it, reduces the concentration of glucose and insulin in the blood.

Drospirenone is a progestogen. It counteracts water retention in the body, and as a result, the occurrence of arterial hypertension, weight gain, breast tenderness, edema.

The drug is also able to normalize lipid metabolism, lower blood cholesterol levels. This medicine can also prevent malignant neoplasms.

What type of pill is Yasmin?

This drug belongs to the group of oral contraceptives, includes hormones of the gonads, their estrogen-progestational fixed combinations.

It is a hormonal drug that contains ethinylestradiol and drospirenone (analogue of natural progestogen).

The contraceptive effect of this drug is based on the interaction of various properties of its constituent substances, the most important of which is the ability to inhibit ovulation and produce a qualitative effect on the endometrium of the uterus.

Drospirenone, if used in therapeutic doses, has antiandrogenic and mild antimineralocorticoid properties.

It is devoid of any estrogenic, glucocorticoid and antiglucocorticoid activity, which provides drospirenone with a pharmacological profile that is very similar to the analogous natural hormone progesterone.

Weak anti-mineralocorticoid properties lead to a weak anti-mineralocorticoid effect.

Who should not take this contraceptive?

This birth control pill is not used if the patient has hypersensitivity (allergy) to one of the components that make up the drug.

This drug should not be used in patients who have:

• vaginal bleeding;
• cancer, benign tumor;
• hepatic, renal failure;
• arterial / venous thrombosis, thromboembolism;
• acute violation of cerebral circulation;
• severe arterial hypertension;
• pancreatitis, liver tumors;
• obesity;
• diabetes;
• migraine;
• pregnancy.

Can I use it during pregnancy and breastfeeding?

This drug is contraindicated for use during pregnancy and breastfeeding.

How to take it?

Take 1 tablet a day at the same time of the day. When taking pills, you should adhere to the sequence indicated on the back of the blister.

The tablets are taken in a row for 21 days. Each next package should be started 7 days after the previous one ends.

Bleeding, similar to menstruation, begins 2-3 days after the end of the pack and may not end before the next pack starts.

If you miss a pill, then the next pill should be taken as soon as you remember about it. The next pill is taken on the next day at the usual time. Moreover, if the break is less than 24 hours, then the contraceptive properties of the drug are not reduced. If the break is more than 24 hours, then the contraceptive effect may be reduced.

If you had an abortion in the first trimester, then the drug is taken on the day of the operation.

If the abortion was performed in the second trimester of pregnancy, or the woman wants to start taking oral contraceptives after childbirth, then she should take the 1st pill on the 21-28th day.

The contraceptive effect is not guaranteed in the first week of use. Therefore, these days, you should use barrier methods of contraception.

The break in use can be less than 4 days but not more than 7 days.

Is Yasmin safe?

Yes, the contraceptive is absolutely safe but if you take too much medication (more than recommended), you can get an overdose.

Overdose with this drug has not yet been observed and described.

Theoretically, an overdose of this drug can cause:

• dyspepsia;
• nausea;
• vomiting;
• vaginal bleeding.

Symptomatic treatment is recommended. No antidote has yet been identified.

Can Yasmin cause side effects?

At the very beginning of treatment, the patient can experience bleeding, smearing discharge from the woman’s vagina, pain in the mammary glands.

In some cases, this drug can cause the following adverse reactions:

• anemia, anorexia, increased appetite, changes in body weight, constipation;
• irritability, depression, emotional instability, tachycardia, phlebitis;
• visual impairment, tinnitus, tremor, vertigo, candidal stomatitis;
• thromboembolism, arterial hypertension, varicose veins, thrombophlebitis, venous thrombosis;
• shortness of breath, abdominal pain, nausea, dyspepsia, vomiting, xerostomia;
• stones in the gallbladder, cholecystitis;
• hirsutism, alopecia, acne;
• urinary tract infections, dysmenorrhea, uterine fibroids, benign tumors in the mammary glands, uterus, cervix;
• swelling, chest pain, chills;
• chloasma, purpura, erythema multiforme.

If you have any unusual side effects after taking this drug, you should consult your doctor about possible changes in the treatment regimen.

Does Yasmin pill make your breasts bigger?

Although this contraceptive can affect your breast size, they don’t change your breast size permanently. Before you start using these pills, make sure you understand how it can affect your body and what side effects it can cause.

Does the pill cause weight gain?

Weight gain is not in the list of common side effects of this medicine. Although weight changes may be a side effect of birth control pills, you likely won’t gain weight with this contraceptive. See your doctor if you have ever had weight problems.

Is this medicine good for skin?

Yasmin is not approved to treat a premenstrual dysphoric disorder. This medicine is approved to help treat moderate acne in females 14 years of age or older who also need oral birth control. It is not approved to treat acne.

Can I take other drugs with Yasmin?

Some products that may interact with this contraceptive:

• atazanavir/cobicistat;
• ospemifene;
• fosamprenavir;
• tamoxifen;
• aromatase inhibitors (such as anastrozole, exemestane);
• tizanidine;
• certain combination products used to treat chronic hepatitis C (ombitasvir/paritaprevir/ritonavir with or without dasabuvir);
• tranexamic acid;
• HIV drugs (such as nelfinavir, nevirapine, ritonavir);
• ACE inhibitors such as enalapril/lisinopril;
• NSAIDs such as ibuprofen/naproxen;
• potassium-sparing “water pills”/diuretics such as eplerenone/spironolactone/triamterene);
• griseofulvin;
• aliskiren;
• angiotensin receptor blockers such as losartan/valsartan, heparin;
• modafinil;
• St. John’s wort;
• rifamycins (such as rifampin);
• drugs used to treat seizures (such as barbiturates, carbamazepine, felbamate, phenytoin, primidone, topiramate).